UPDATED Skybailey's Cryomedicine guide (Stable Branch)

An update to Skybailey's Cryomedicine Guide (Stable Branch):
Fixed where I was wrong about the NRL and the recipes a little:

Hello! This guide is only valid for upstream servers. It serves as a general overview on when and how to use what is a very underrated medical system. Last updated: 6/23/2025
(Vulture has significantly changed what cryox does, making cryo have a more much more specific use case.)

OVERVIEW:

Cryo is INCREDIBLY powerful when used, and outperforms normal meds in treating moderately to severely injured people suffering from wide variety of inflictions quickly, cheaply, and efficiently using only one chem, while also serving as the best way to revive severely injured corpses. Only way to heal toxin on corpses or reverse corpse rot!

The chems below are listed in order of priority they should be made. Most stations start with 100u of Cryox. Cryochems will never overdose.

Cryox: One and done with a dirt cheap chem!

The most basic and cheap chem, Cryoxadone is an incredibly cheap chem that’s a more potent form of Omni. Atmos has an even cheaper recipe that they could make, if convinced, that makes it effectively free and infinite.

Example Doses
Units used → 5u 15u 30u 45u
Airloss (highest type value) 30 90 180 >200
Brute (highest type value) 13 39 78 117
Burn (highest type value) 15 45 90 135
Toxin (highest type value) 20 60 120 180
Treatment time 10s 30s 60s 90s
Recipes

Chemstation Recipe:
1u Dexalin + 1u Water +1u Oxygen → Mix → 3u Cryoxadone
Atmos Recipe:
67% o2 33% water vapor, then pipe plasma in using volume pump at .01 into condenser. Plasma is a catalyst that is not used by this process. Pretty much infinite, free cryox once made.

Alox: Body with 2k burns from science? No problem!

The fairly cheap Aloxadone is by far the best way to solve dead bodies with severe burns. Needs some Aloe from Botany.

Example Doses

Use enough to get within Defib Range (<200 total damage)

Units used → 10u 40u 105u 165u
Non-caustic burns 80 320 840 1320
Caustic 30 120 315 495
Treatment time 20s 1.3m 3.5m 5.5m
Recipe

Chemstation Recipe:
2u Cryoxadone + 1u Aloe + 2u Leporazine → Mix → 4u Aloxadone

Necro: Severe blunt or toxin on dead.

The moderately expensive chem Necrosol will quickly heal large amounts of blunt, burn, and poison on dead bodies. Needs Omnizine, but it’s efficient with it.

Example Doses

Use enough to get within Defib Range (<200 total damage)

Units used → 5u 15u 30u 60u 120u
Brute (any) 13 39 78 156 312
Burn (any) 12 36 72 144 288
Poison 20 60 120 240 480
Treatment time 10s 30s 1m 2m 4m
Recipe

Chemstation Recipe:
3u Blood + 1u Omnizine + 2u Cryoxadone → Heat (short) → 2u Necrosol

Oppo: Rot Begone!

Opporozidone, while very expensive, is rarely used in large amounts and allows for the reversal and revival of rotted corpses. Allows you to resurrect a rotted corpse without cloning. This is great for MRP as it allows the revived character to remember their past life IC (Cloning wipes everything, and MMI, well, no hands).

How to dose it

Reduces rot by 3.3m per 5u dose. Use small doses at a time, 5u every 10 seconds until no longer rotted.

Recipe

Chemstation Recipe:
1u Cognizine + 2u Plasma + 1u Doxarubixadone → Heat (long) → 3u Opporozidone

Doxa: In case of space cancer...

Doxarubixadone is usually not used much, only because cellular is rare. It however is VERY good at healing cellular, being by far the best option in town. Usually overkill but nice to have, as it’s not too expensive.

Example Doses
Units used → 5u 15u 30u
Cellular) 20 60 120
Treatment time 10s 30s 1m
Recipe

Chemstation Recipe:
1u Cryoxadone + 1u Unstable Mutagen → Mix → 2u Doxarubixadone

Less attention once set up:

Cryo has the benefit of only requiring attention from the treating doctor twice: when beginning and finishing treatment, allowing more attention to be dedicated to other patients, and to allow just one doctor focused on cryo to deal with as many patients as they have tubes.

Setup and tips

What you start with:

Every station starts with at least a 2 Cryotube setup almost ready to use; with a main loop already connected to Distro and Waste (or a waste container), sometimes even starting with slots for backup tanks.
Cryo systems use a closed air loop, where cold air is circulated, with waste being taken out and new air being added when needed

Simple Setup

First, turn on the distro-in pump, setting it to 200kPa. Higher and you risk over-pressurizing if the system were to heat up, but high pressures cool faster. Risky to go above 300kPa. If distro isn’t on yet, you can connect a backup tank to the system and set its output. You can check by using a Gas Analyzer on the pod, or by entering and seeing if you suffocate.
Next, turn on the freezer to 70K. Any lower than 100K tends to be overkill, but this makes sure cooling happens at a good rate while reducing post-cryo recovery time.
Next, turn on the waste filter. Output pressure should be maxed, and set to CO2 (Swap to NO2 if patient is a slime/vox etc.). Note: A good amount of breathed out waste can build up before it becomes toxic, so this isn’t needed in a pinch.
Finally, turn on the Cryopod. It’s ready for use!

Extra, optional setup

If Distro isn’t on, or if you think it is at risked to be turned off/sabotaged, set up a backup tank using a Connector Port. An air canister is recommended, as it has both nitrogen and oxygen.
Oxygen is toxic to Vox; once you have time to, set up a filter to the incoming line that can be set to filter in only nitrogen so you can accommodate them. They can also use internals with a Nitrogen Tank in a pinch, but this is suboptimal
A backup LV, JPACMAN generator might be wanted. Cryo uses some power when active, but not too much. Energy is only required to cool the air loop and inject chemicals


Treating living patients

For living, critical or non critical patients, Cryox is the go-to treatment solution. It treats everything but cellular quickly and cheaply.

Inserting

When adding a patient to a Cyrotube, first make sure they have no open wounds. Then, remove any insulating clothing, i.e. hard suits. Placing these in a locker is recommended to prevent thieving. After checking to make sure they are not vox, toggle off their internals, and add them to the tube. Quickly calculate how much Cryox you need to add, then add it to a beaker and insert. Sometimes some saline to restore blood level is nice too.
Cryox never OD’s and is cheap, so if there is excess you can just add a full beaker to the tube, removing the beaker when their injuries are a bit over 50% healed.
Chems are added at 1u/s, but consumed at 0.5u per second by patients.

Post care!

When they are ready to remove, remove them, give them any previously removed clothing, and administer 2u of Lepo or 5u of Dylo. Lizards and slimes take more cold damage, so using Lepo is recommended. If no anti-cold chems are available, non-cold vulnerable species will be fine with <6 cold damage. This can be treated with topicals if you want.


Treating dead patients

Cryo gives the best options for many types of damage on dead bodies, the only option for poison, and the only way to reverse rot. Make sure to place dead bodies waiting for cryo on stasis beds or in body bags to prevent rot from progressing. Rot doesn’t progress when a body is frozen.

Inserting

When adding a patient to a Cyrotube, just remove any insulating clothing, i.e. hard suits. Placing these in a locker is recommended to prevent thieving. Make sure they are not Vox, and add the required amount of chems to bring to defibrillation range. You can mix as many as you like. Calculate the time required until they are in range (units of largest quantity chem added x2 in seconds)

When ready to defib...

When they are ready to remove, there is one step that can be done to make them recover much quicker; right after removed, place a beaker with Cryox into the cryotube then use defibs on the patient. As soon as the patient has been revived, stick them directly back into tube so Cryox can heal them to full. If you dally too much on reinserting them, asphyxiation and cold can kill them again. From then on out, treat them as you would any other Living Patient.

Rotted Corpses

Healing rotted corpses is a rarely done process, requiring hard to acquire Oppo. Often in LRP it is easier to Clone someone, but in MRP it’s very useful as it allows for their character to retain their memories from before they died (Still cannot remember the events leading up to their death, but their character’s other memories will still be intact, unlike with cloning). Borging is also an option if they don’t want hands. See the section on Oppo for how to administer doses. Once they are no longer rotted, treat them like any other dead cryo patient.

may want to clarify that lizards need the space equalization chemical and winter gear, the chemical is called leporazine. 30th chemical in medicine category on wiki. link to chem wiki: Chemistry - Space Station 14 Wiki

Already in there under post care:

Lizards and slimes take more cold damage, so using Lepo is recommended. If no anti-cold chems are available, non-cold vulnerable species will be fine with <6 cold damage. This can be treated with topicals if you want.

Winter gear can help some, but Lepo is easy to make, and by the time they finish putting on the winter gear the worst of the cold is over in my experience.

ah nice, just wanted to make sure because as a occasional reptilian player, this happens a lot to me when they do cryogenic treatments